Examined lymph node counts affected the staging and survival in cervical cancer: a retrospective study using the SEER and Chinese cohort.

ABSTRACT:

Background

The impact of examined lymph node (LN) count on survival in cervical cancer remains understudied, with no consensus on the optimal number required.

Objectives

We aimed to investigate the role of LN count in postoperative pathological evaluation for cervical cancer patients undergoing surgery.

Methods

Data from the US SEER database and a retrospective Chinese cohort were analyzed. Multivariable logistic and Cox regression models assessed LN positivity detection and overall survival (OS), respectively. Smoothing spline curves and Chow tests identified structural change points in hazard ratios and LN-positive ratios.

Results

Among 14,133 SEER and 2,811 Chinese cases, higher LN counts correlated with increased detection of positive LNs (OR: 1.040, 95% CI

SUBMITTER: Guo T 

PROVIDER: S-EPMC11792132 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature