PretoxTM: a text mining system for extracting treatment-related findings from preclinical toxicology reports.

ABSTRACT: Over the last few decades the pharmaceutical industry has generated a vast corpus of knowledge on the safety and efficacy of drugs. Much of this information is contained in toxicology reports, which summarise the results of animal studies designed to analyse the effects of the tested compound, including unintended pharmacological and toxic effects, known as treatment-related findings. Despite the potential of this knowledge, the fact that most of this relevant information is only available as unstructured text with variable degrees of digitisation has hampered its systematic access, use and exploitation. Text mining technologies have the ability to automatically extract, analyse and aggregate such information, providing valuable new insights into the drug discovery and development process.

SUBMITTER: Corvi J 

PROVIDER: S-EPMC11792311 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature