The Use of Fluorescent Markers to Detect and Delineate Head and Neck Cancer: A Scoping Review.

ABSTRACT:

Objectives

The aim of surgery for head and neck squamous cell carcinoma (HNSCC) is to achieve clear resection margins, whilst preserving function and cosmesis. Fluorescent markers have demonstrated potential in the intraoperative visualisation and delineation of tumours, such as glioma, with consequent improvements in resection. The purpose of this scoping review was to identify and compare the fluorescent markers that have been used to detect and delineate HNSCC to date.

Methods

A literature search was performed using the Ovid MEDLINE, Ovid Embase, Cochrane CENTRAL, ClinicalTrials.gov and ICTRP databases. Primary human studies published through September 2023 demonstrating the use of fluorescent markers to visualise HNSCC were selected and reviewed independently by two auth

SUBMITTER: Srinivasan A 

PROVIDER: S-EPMC11792437 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature