Exploring the functional diversity and metabolic activities of the human gut microbiome in Thai adults in response to a prebiotic diet.

ABSTRACT: Exploring dietary methods to alter microbial communities and metabolic functions is becoming an increasingly fascinating strategy for improving health. Copra meal hydrolysate (CMH) is alternatively used as a gut health supplement. However, the functional diversity and metabolic activities in gut microbiome in relation to CMH treatment remain largely unknown. Therefore, this study aimed to identify key predominant groups of bacterial species toward diversified metabolic functions, activities, and routes using metaproteomics. As a result, the integrative analysis of metaproteomic data revealed that seven key families across 11 dominant gut bacterial species were concerted. Consistently, across 76,206 proteins assigned to the metabolism of the 255,964 annotated proteins, short-chain fatty aci

SUBMITTER: Kingkaw A 

PROVIDER: S-EPMC11792504 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature