<i>mtlA,</i> a novel typing gene offering enhanced resolution for pandemic <i>Vibrio</i> species.

ABSTRACT: The gene mtlA, encoding the mannitol transporter subunit IICBA of the phosphotransferase system, was the core gene with the greatest variability in Vibrio parahaemolyticus and could be used as a new typing marker in Vibrio parahaemolyticus. To expand its application, we performed an evolutionary analysis and found that the mtlA gene was present in nine phyla, 371 genera, and 1,662 species of bacteria. It is commonly found in pathogenic species of Vibrio, followed by Paenibacillus, Mycolicibacterium, etc. To investigate whether the mtlA gene could serve as a novel typing gene for whole Vibrio species, we compared the typing effect of the mtlA gene with multilocus sequence type (MLST) in 13 common pathogenic Vibrio

SUBMITTER: Zhou L 

PROVIDER: S-EPMC11792507 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature