The grapevine ABC transporter B family member 15 is a trans-resveratrol transporter out of grapevine cells.

ABSTRACT: Stilbenes, particularly trans-resveratrol, play a highly relevant defense role in grapevines as phytoalexin is induced in response to stress. Metabolism and transport of stilbenes can be conveniently investigated in grapevine cell culture since large amounts of trans-resveratrol are accumulated in the extracellular medium upon treatment with the elicitor methylated cyclodextrin, either alone or combined with methyl jasmonate. A proteomic approach on grapevine cell membrane fractions was performed to find trans-resveratrol transporter candidates. The candidate VvABCB15 was functionally characterized. Its stable expression in both yeast and Silybum marianum cells' heterologous systems led to increased trans-resveratrol transport in these hosts. Transient ex

SUBMITTER: Martinez-Marquez A 

PROVIDER: S-EPMC11792551 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature