Atypical early neural responses to native and non-native language in infants at high likelihood for developing autism.

ABSTRACT:

Background

Language difficulties are common in autism spectrum disorder (ASD), a neurodevelopmental condition characterized by impairments in social communication as well as restricted and repetitive behaviors. Amongst infant siblings of children with an ASD diagnosis - who are at higher likelihood for developing ASD - a high proportion also show difficulties and delays in language acquisition.

Methods

In this study, we used functional magnetic resonance imaging (fMRI) to examine differences in language processing in 9-month-old infants at high (HL) and typical (TL) familial likelihood for ASD. Infants were presented with native (English) and novel (Japanese) speech while sleeping naturally in the scanner. Whole-brain and a priori region-of-interest analyses were conducted t

SUBMITTER: Wagner L 

PROVIDER: S-EPMC11792659 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature