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Albumin-bilirubin score: a promising predictor of postoperative distant metastasis in patients with colorectal cancer.


ABSTRACT:

Aim

The objective of this study was to investigate the prognostic significance of the preoperative serum albumin-bilirubin (ALBI) score in patients with colorectal cancer (CRC).

Methods

Preoperative ALBI data from 1506 CRC patients were categorized into high-value and low-value groups, and the clinicopathological characteristics of these groups were compared. A Cox proportional hazards regression model was employed to investigate the risk factors associated with distant metastasis. The Kaplan-Meier method and log-rank test were utilized to analyze the relationship between ALBI scores and 5-year distant metastasis-free survival (DMFS).

Results

The incidence of distant metastasis in group B (ALBI ≥ -2.4) was significantly higher at 28.81% compared to group A (ALBI < -2.

SUBMITTER: Shi X 

PROVIDER: S-EPMC11792804 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature