Associations between oxidation balance score and abdominal aortic calcification, and the mediating role of glycohemoglobin: a nationally representative cross-sectional study from NHANES.

ABSTRACT:

Background

Abdominal aortic calcification (AAC) is prevalent among middle-aged and elderly populations, elevating the risk of cardiovascular and cerebrovascular events. Leveraging data from the National Health and Nutrition Examination Survey (NHANES), we conducted a nationally representative cross-sectional study. Our aim was to evaluate whether subjective interventions could influence AAC scores by modifying the antioxidant/pro-oxidant status of individuals and to investigate the role of glycohemoglobin in this relationship.

Methods

The study analyzed data from 1,600 U.S. adults. The study used oxidation balance score (OBS) as an exposure variable derived from 16 dietary and 4 lifestyle factors, as well as glycohemoglobin obtained from blood tests. The main outcome measure

SUBMITTER: Liu H 

PROVIDER: S-EPMC11792858 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature