Assessing the therapeutic potential of vagus nerve stimulation in autoimmune diseases: A systematic review.

ABSTRACT: Emerging evidence suggests that the vagus nerve can modulate the immune system in experimental settings. Vagus nerve stimulation (VNS), initially developed for managing epilepsy, is now being explored as a treatment for autoimmune diseases due to its potential immunomodulatory effects. This systematic review evaluates the therapeutic potential of VNS in autoimmune diseases by critically appraising findings from human clinical studies. This systematic review was conducted in accordance with the PRISMA guideline, with a comprehensive literature search performed in Ovid, Cochrane, and PubMed databases up to July 2024. Studies focusing on VNS in patients with autoimmune diseases were eligible, and the quality of study was assessed using the QualSyst tool. Of the 53 papers identified for full-t

SUBMITTER: Chan E 

PROVIDER: S-EPMC11793006 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature