Left Atrial Mechanical Dysfunction and the Risk for Ischemic Stroke in People Without Prevalent Atrial Fibrillation or Stroke : A Prospective Cohort Study.

ABSTRACT:

Background

Atrial myopathy-characterized by changes in left atrial function and size-may precede and promote atrial fibrillation (AF) and cardiac thromboembolism. In people without prior AF or stroke, whether analysis of left atrial function and size can improve ischemic stroke prediction is unknown.

Objective

To evaluate the association of echocardiographic left atrial function (reservoir, conduit, and contractile strain) and left atrial size (left atrial volume index) with ischemic stroke and determine whether these measures can improve the stroke prediction achieved by CHA₂DS₂-VASc score variables.

Design

Prospective cohort study.

Setting

ARIC (Atherosclerosis Risk in Communities) study.

Participants

4917 ARIC participants withou

SUBMITTER: Maheshwari A 

PROVIDER: S-EPMC11793084 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature