A Pilot Study Using a Smartwatch to Search for Biomarkers of Heart Rate Variability in Active Ulcerative Colitis.

ABSTRACT:

Introduction

Autonomic imbalance has been reported to correlate with clinical remission in patients with ulcerative colitis (UC). This study evaluated heart rate variability (HRV), a potential digital biomarker, in patients with active UC using a smartwatch that is easy to handle.

Methods

Patients with active UC were recruited for this prospective study. The patients' HRV was measured via the Fitbit Inspire2^™ linked via Bluetooth to their smartphone. HRV during nighttime sleep was obtained from continuous data. Patients were required to input the Simple Clinical Colitis Activity Index (SCCAI) score once daily by the application on their smartphones for 3 months.

Results

Nine patients with UC were included. In clinically active disease, SCCAI scores showed a

SUBMITTER: Imai J 

PROVIDER: S-EPMC11793913 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature