A 32-year trend analysis of lower respiratory infections in children under 5: insights from the global burden of disease study 2021.

ABSTRACT:

Objectives

Lower respiratory infections are the most significant health threat to children under 5 years old, leading to the highest disease burden across all age groups. This study aims to provide an up-to-date assessment of the global burden of lower respiratory infections in children under 5 years of age.

Methods

This study utilizes data and methodologies from the Global Burden of Disease Study 2021 to analyze changes in the burden of lower respiratory infections from 1990 to 2021, focusing on incidence, mortality, and disability-adjusted life years. A jointpoint model is employed to calculate trends and the average annual percentage change in the disease burden among children under 5 years old over the period 1990-2021. Additionally, frontier analysis is used to visually

SUBMITTER: Wang Y 

PROVIDER: S-EPMC11794078 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature