Nonlinear association between depressive symptoms and homeostasis model assessment of insulin resistance: a cross-sectional analysis in the American population.

ABSTRACT:

Background

Depressive symptom, a pervasive mental health disorder, has garnered increasing attention due to its intricate interconnections with various physiological processes. One emerging avenue of investigation delves into the potential association between depressive symptom and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR), a parameter reflecting insulin resistance. The intricate interplay between these two domains holds promising implications for understanding the multifaceted nature of depressive symptom and its impact on metabolic health.

Methods

We used weighted multivariable logistic regression models with subgroup analysis to explore the relationship between depressive symptom and homeostasis model assessment of insulin resistance. Non-linear correla

SUBMITTER: Jiang C 

PROVIDER: S-EPMC11794198 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature