Gut microbiota in patients with sarcopenia: a systematic review and meta-analysis.

ABSTRACT:

Background

Intestinal dysbiosis was considered a pivotal pathological mechanism underlying sarcopenia. Despite the fervor surrounding research in this domain, substantial controversy persists regarding the obtained outcomes.

Objective

To systematically summarized the disparities in gut microbiota composition between the group afflicted by sarcopenia and non-sarcopenia controls.

Methods

PubMed, Medline, CINAHL, EMBASE, Scopus, Web of Science and Google Scholer, Cochrane Library and gray literature sources were systematically searched for in randomized controlled trials. Meta-analysis and random-effects meta-regression were conducted using Rev. Man 5.3. Overall effect was measured using Hedges's g and determined using Z-statistics. Cochran's Q test and I <

SUBMITTER: Wang G 

PROVIDER: S-EPMC11794218 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature