Deep brain stimulation of the hypothalamic region: a systematic review.

ABSTRACT:

Background

Deep brain stimulation (DBS) has been successfully used for the treatment of circuitopathies including movement, anxiety, and behavioral disorders. The hypothalamus is a crucial integration center for many peripheral and central pathways relating to cardiovascular, metabolic, and behavioral functions and constitutes a potential target for neuromodulation in treatment-refractory conditions. To conduct a systematic review, investigating hypothalamic targets in DBS, their indications, and the primary clinical findings.

Methods

PubMed, Scopus, and Web of Science databases were searched in accordance with the PRISMA guideline to identify papers published in English studying DBS of the hypothalamus in humans.

Results

After screening 3,148 papers, 34 studies consi

SUBMITTER: Mofatteh M 

PROVIDER: S-EPMC11794333 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature