Quantification of hemi-hepatic ischemia using real-time multispectral oxygenation imaging with single snapshot imaging of optical properties (SSOP).

ABSTRACT:

Background

Identifying liver ischemia is crucial in liver surgery. This study aimed to develop a hemi-hepatic ischemia model for assessing liver ischemia using single snapshot imaging of optical properties (SSOP), a noninvasive optical imaging modality that provides real-time measurements of tissue oxygen saturation (StO2).

Materials and methods

Twelve swine were randomly assigned to two groups: One undergoing total vascular inflow occlusion (TVIO) and the other undergoing hepatic artery occlusion (HAO). Preoperative 3D CT scans were used to locate the left-sided hepatic arteries and portal veins, which were clamped during surgery. Real-time SSOP imaging was conducted to measure StO₂ in three lobes-the left lateral lobe (LL), left medial lobe (LM), and right media

SUBMITTER: Mishima K 

PROVIDER: S-EPMC11794345 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature