Novel subharmonic-aided pressure estimation for identifying high-risk esophagogastric varices.

ABSTRACT:

Background

Subharmonic-aided pressure estimation (SHAPE) is a technique for determining changes in ambient pressure. We aimed to analyze a novel SHAPE integrated into ultrasound diagnostic equipment to predict patients with liver cirrhosis at high risk of esophagogastric varices (EV).

Methods

This prospective study included 111 patients with liver cirrhosis diagnosed between 2020 and 2023. We obtained liver stiffness measurements (LSM) and spleen stiffness measurements (SSM) using shear wave elastography and hepatic vein-portal vein (HV-PV) gradient using the SHAPE method. The EV risk was determined either as null, low, or high by esophagoscopy and Child-Pugh stage.

Results

HV-PV gradient increased concordantly with the increase in EV risk (- 7.0 dB in null-risk, - 4.

SUBMITTER: Kuroda H 

PROVIDER: S-EPMC11794364 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature