Choriocapillaris flow in two different patterns of exudative type 1 macular neovascularization.

ABSTRACT:

Background

To compare the characteristics of type 1 macular neovascularization (MNV) and the surrounding choriocapillaris (CC) perfusion in patients with neovascular age-related macular degeneration (nAMD) versus those with pachychoroid neovasculopathy (PNV) using swept-source optical coherence tomography angiography (SS-OCTA).

Methods

This retrospective study included 64 treatment-naïve eyes (37 nAMD, 27 PNV) with type 1 MNV. SS-OCTA images were analysed to measure MNV area and perimeter, and CC flow deficits (FD) in five concentric rings surrounding the lesion. CC FD percentage (FD%), area (FDa), and number (FDn) were quantified. Intervortex anastomoses presence was also assessed.

Results

MNV lesions in nAMD were significantly larger in area (2.94 vs 1.56 mm², p = 0

SUBMITTER: Viggiano P 

PROVIDER: S-EPMC11794458 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature