Clinical features, treatment, and prognosis of zoledronic acid-induced uveitis.

ABSTRACT:

Background

Uveitis is a rare ocular adverse reaction of zoledronic acid, the specific clinical features are not clarified. This study was to investigate the clinical features of zoledronic acid-induced uveitis and provide reference for rational use of zoledronic acid.

Methods

We collected clinical data on zoledronic acid-induced uveitis for retrospective analysis by searching Chinese and English data up to October 31, 2024.

Results

Uveitis occurred in 44 patients with a median age of 66.5 years (range 47, 87) and 93.2% in females. The median time to onset of uveitis was 48 h (range 10, 192). Eye pain (86.4%), decreased vision (61.4%), and redness (50.0%) were the most commonly described symptoms. Uveitis could involve unilateral eyes (68.2%) and bilateral eyes (31.8%)

SUBMITTER: Wu Z 

PROVIDER: S-EPMC11794653 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature