Incidence of hip problems in developmental central hypotonia: A scoping review.

ABSTRACT:

Aim

To describe what is known about hip problems in individuals with developmental central hypotonia.

Method

Searches were conducted in five databases to October 2023. Down syndrome was excluded from this analysis of less well-known genetic diagnoses. At least two reviewers independently screened titles, abstracts, read full-text articles, and extracted data.

Results

Of 89 full-text articles, 79 met inclusion criteria. Studies included 544 individuals aged 1 month to 63 years with Kabuki, 49, XXXXY, Prader-Willi, PURA, Koolen de Vries, Emanuel, TRPM3, Wolf-Hirschhorn, and other rare syndromes. Most diagnoses may be associated with a combination of differences in hip structure or stability that are evident at birth, or develop in early infancy, with increasing hip dysp

SUBMITTER: Livingstone RW 

PROVIDER: S-EPMC11794678 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature