Primary scleral buckling vs. vitrectomy for stage 4A retinopathy of prematurity: a systematic review and meta-analysis of surgical outcomes.

ABSTRACT:

Topic

To compare anatomic outcomes of primary scleral buckle (SB) vs. lens sparing pars plana vitrectomy (LSV) in treating retinopathy of prematurity (ROP) associated Stage 4A retinal detachment (RD).

Clinical relevance

ROP is the leading cause of blindness in childhood in industrialized countries worldwide. ROP eyes with Type 1 disease can progress into tractional retinal detachment with or without a rhegmatogenous component despite early medical management with retinal ablation and/or intravitreal anti-VEGF injections, necessitating surgical management.

Methods

This systematic review and meta-analysis was registered with the Open Science Framework. A PubMed literature search was performed, and ROP-associated Stage 4A RD studies were selected based on preset inclusio

SUBMITTER: Saeed OB 

PROVIDER: S-EPMC11794751 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature