Identification of a comprehensive set of transcriptional regulators involved in the long-term survivability of Escherichia coli in soil.

ABSTRACT: Bacteria that typically do not thrive in soil can survive therein for long periods. While much research has been conducted on the external environmental factors affecting the long-term survival of bacteria in soil, their inherent factors are poorly understood. To adapt to environmental changes, bacteria alter their gene expression patterns using transcriptional regulators such as sigma factors. Using Escherichia coli as a model bacterium, we examined the effects of each transcriptional regulator on the long-term survivability of E. coli in soil. The survivability of 294 E. coli strains deficient in transcriptional regulators in soil was measured over 6 weeks. The results showed that ten strains deficient in transcription factors significantly reduced survivability, whereas four deficient s

SUBMITTER: Nakamoto S 

PROVIDER: S-EPMC11794783 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature