Adaptive treatment workflow and dosimetric evaluation of intracranial fractionated stereotactic radiosurgery on a low-field magnetic resonance-linear accelerator.

ABSTRACT:

Background and purpose

Online adaptive radiotherapy for fractionated intracranial stereotactic radiosurgery (FSRS) on a magnetic resonance linear accelerator (MR-L) has the potential to allow for real-time adjustments of anatomical changes during radiotherapy treatment. This study investigates the dosimetric improvements of an online-adaptive MR-L workflow and validates the dosimetry utilizing an MR-visible phantom.

Methods and materials

Twenty-six cases previously treated with a conventional C-arm linear accelerator (CA-L) were replanned to determine optimal optimization constraints and objectives for achieving comparable MR-L plans. The optimization methodology was subsequently applied to simulate an online adaptive workflow on an MR phantom, incorporating target volumes f

SUBMITTER: Snyder KC 

PROVIDER: S-EPMC11795098 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature