Sticky tubes co-assembled by functionalised diphenylalanine and polydopamine nanoparticles form biocompatible antifouling coating.

ABSTRACT: The persistent challenge of biofouling, driven by the accumulation of microorganisms and biological residues on surfaces, undermines operational efficiency and safety across multiple industries. Functionalized peptide based biocompatible and supramolecular coating can provide a substantial solution to this crucial issue. This present study describes the formation of polydopamine-comprised sticky tubes through the co-assembly of an antifouling peptide P1 (FF-PFB) and Polydopamine Nanoparticles (PDA NPs) with an adhesive catechol moiety. To overcome the synthetic complications associated with the attachment of adhesive l-DOPA or dopamine with antifouling peptides, we have employed a simple co-assembly strategy. These co-assembled sticky tubes form a stable, biocompatible coating on desired s

SUBMITTER: Sivagnanam S 

PROVIDER: S-EPMC11795260 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature