Mapping glioma's impact on cognition: Insights from macrostructure, microstructure, and beyond.

ABSTRACT:

Background

Cognitive impairment (CI) significantly impacts the quality of life of glioma patients. The main contributing risk factors include tumor characteristics, treatment-related factors, and their complex interplay. This review explores the role of advanced structural neuroimaging techniques in understanding CI in glioma patients.

Methods

A literature search was conducted in PubMed, PsycINFO, and ISI Web of Knowledge using specific keywords. We included studies with advanced magnetic resonance imaging techniques and objective neuropsychological exams.

Results

At diagnosis, during the pre-surgery phase, associations between glioma characteristics and cognitive outcomes have been described. Specifically, patients with isocitrate dehydrogenase (IDH)-wild-type glioma

SUBMITTER: Cayuela N 

PROVIDER: S-EPMC11795312 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature