Delving into discrepancies, a single-center experience with Accelerate Pheno for gram-negative bacteremia, a rapid phenotypic susceptibility testing method.

ABSTRACT:

Objective

Discrepancies or inaccuracies between testing methods can create confusion or lead to clinical harm if antibiotics are inappropriately chosen. We report our clinical experience using the Accelerate Pheno™ followed by routine automated susceptibilities by the Vitek®2 for positive blood cultures with gram-negative rods.

Design

This was a retrospective review of positive gram-negative blood cultures, including comparison of susceptibility testing results and impact on clinical care.

Setting

Academic teaching hospital.

Patients participants

All patients admitted to the hospital with gram-negative bacteremia from January 2020 to December 2022.

Methods

Microbiology was reviewed for discrepancies as defined by very major errors (VMEs), major errors (M

SUBMITTER: Freeman Weiss Z 

PROVIDER: S-EPMC11795440 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature