Advances in tissue engineering of peripheral nerve and tissue innervation - a systematic review.

ABSTRACT: Although various options are available to treat injured organs and peripheral nerves, none is without limitations. Auto- and allografts are the first choice of treatment, but tissue survival or functionality is not guaranteed due to often limited vascular and neural networks. In response, tissue-engineered solutions have been developed, yet clinical translations is rare. In this study, a systematic review was performed on tissue-engineered advancements for peripheral nerves and tissues, to aid future developments in bridging the gap toward the clinic by identifying high-potential solutions and unexplored areas. A systematic search was performed in PubMed, Embase, Web of Science, and Scopus until November 9, 2023. Search terms involved "tissue engineering," "guided," "tissue scaffold," and

SUBMITTER: Sueters J 

PROVIDER: S-EPMC11795627 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature