Postprandial Effects of Four Test Meals Containing Wholegrain Rye or Refined Wheat Foods on Circulating Incretins, Ghrelin, Glucose, and Inflammatory Markers.

ABSTRACT:

Background

High intake of whole grains has consistently been associated with reduced risk of obesity, coronary artery disease, and type 2 diabetes. Dietary interventions have shown beneficial metabolic effects of whole grains, but the metabolic response varies with different types of cereals.

Objectives

We evaluate the metabolic effects of substituting refined wheat with wholegrain rye foods within a complex diet, examining the day-long postprandial response of glucose-dependent insulinotropic peptide (GIP), glucagon-like peptide-1 (GLP-1), ghrelin, glucose, and inflammatory biomarkers in individuals with overweight and obesity.

Methods

Twenty-nine healthy adults with body mass index of 32 ± 9 kg/m² were randomly assigned to 3 intervention days, separated b

SUBMITTER: Aberg S 

PROVIDER: S-EPMC11795698 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature