Extensive paralogism in the environmental pangenome: a key factor in the ecological success of natural SAR11 populations.

ABSTRACT:

Background

The oceanic microbiome is dominated by members of the SAR11 clade. Despite their abundance, challenges in recovering the full genetic diversity of natural populations have hindered our understanding of the eco-evolutionary mechanisms driving intra-species variation. In this study, we employed a combination of single-amplified genomes and long-read metagenomics to recover the genomic diversity of natural populations within the SAR11 genomospecies Ia.3/VII, the dominant group in the Mediterranean Sea.

Results

The reconstruction of the first complete genome within this genomospecies revealed that the core genome represents a significant proportion of the genome (~ 81%), with highly divergent areas that allow for greater strain-dependent metabolic flexibility. The fle

SUBMITTER: Molina-Pardines C 

PROVIDER: S-EPMC11796062 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature