Associations between depressive and anxiety symptoms and incident kidney failure in patients with diabetic nephropathy.

ABSTRACT:

Objective

This study aimed to analyze the associations between depressive and anxiety symptoms and risk of incident kidney failure in patients with biopsy-proven diabetic nephropathy (DN).

Methods

This retrospective study enrolled 241 type 2 diabetic patients with biopsy-proven DN. Huaxi Emotional-Distress Index (HEI) was used to evaluate the depression and anxiety status of patients on admission. According to the HEI score, DN patients were divided into HEI score ≤ 8 group (without depression and anxiety) and HEI score > 8 group (with depression and anxiety). The study endpoint was defined as progression to kidney failure. The cox proportional hazard analysis was performed to investigate the risk factors for progression to kidney failure in DN patients.

Results

Twent

SUBMITTER: Qin C 

PROVIDER: S-EPMC11796097 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature