Association between oxidative balance score and gallstone disease: a population-based study from NHANES.

ABSTRACT:

Background

Oxidative stress has been reported to participant in the pathogenesis of gallstones. Oxidative balance score (OBS) represents pro-oxidant and antioxidant exposures to diet and lifestyle, closely associated with multiple metabolic disorders. However, the relationship between OBS and gallstones remains unclear.

Methods

This study analyzed cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) 2017-2020. OBS was calculated based on the 24-h recall interviews or questionnaires. We used weighted logistic regression, restricted cubic splines (RCS), weighted quantile sum (WQS) regression and the Bayesian kernel machine regression (BKMR) model to identify the relationship between OBS and gallstones. Subgroup analysis and sensitivity analys

SUBMITTER: Zhang M 

PROVIDER: S-EPMC11796620 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature