Diagnosis and prognosis of pancreatic cancer with immunoglobulin heavy constant delta blood marker.

ABSTRACT:

Background

Pancreatic cancer (PC) is highly malignant and difficult to detect, while few blood markers are currently available for diagnosing PC.

Methods

We obtained differential expression genes (DEGs) from GEO (gene expression omnibus) database and assessed by quantitative real-time polymerase chain reaction (qRT-PCR), receiver operating characteristic (ROC), univariate and multifactorial regression analysis, and survival analysis in our clinic center. Through the TCGA (the cancer genome atlas) database, we analyzed functional enrichment, different risk groups with survival analysis, immunological features, and the risk score established by the Cox regression model and constructed a nomogram.

Result

Immunoglobulin heavy constant delta (IGHD) was remarkably upregulat

SUBMITTER: Chen Q 

PROVIDER: S-EPMC11797196 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature