The diurnal pattern of cytokines, chemokines and growth factors in human saliva-a pilot study.

ABSTRACT:

Background

Understanding of possible periodicity of cytokines, chemokines and growth factors is of great interest and provide valuable information for research into pathophysiological mechanism of inflammatory disease and chronic pain. Significant efforts have been made to identify different analytes in saliva. For precision and accuracy in measurement and interpretation of results, it is crucial to know the source of variability, especially the circadian variation for the analytes.

Objective

The study aimed to analyze circadian variation in 71 inflammatory markers in both unstimulated and stimulated saliva, as well as plasma, from a sample of healthy individuals.

Methods

Ten young adults participated. Unstimulated and stimulated whole saliva were collected at 3-h int

SUBMITTER: Jasim H 

PROVIDER: S-EPMC11797753 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature