Determination of positive end-expiratory pressure in COVID-19-related acute respiratory distress syndrome: A systematic review.

ABSTRACT:

Background

The impact of high positive end-expiratory pressure (PEEP) ventilation and the optimization of PEEP titration in COVID-19-induced acute respiratory distress syndrome (ARDS) continues to be a subject of debate. In this systematic review, we investigated the effects of varying PEEP settings on patients with severe ARDS primarily resulting from COVID-19 (C-ARDS).

Objectives

Does higher or lower PEEP improve the outcomes in COVID-19 ARDS? Does individually titrated PEEP lead to better outcomes compared with PEEP set by standardised (low and high ARDS network PEEP tables) approaches? Does the individually set PEEP (best PEEP) differ from PEEP set according to the standardised approaches (low and high ARDS network PEEP tables)?

Design

Systematic review of observa

SUBMITTER: Sachkova A 

PROVIDER: S-EPMC11798381 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature