Methods of identifying surgical Necrotizing Enterocolitis-a systematic review and meta-analysis.

ABSTRACT:

Background

Current data suggests potential benefit of earlier surgery for necrotizing enterocolitis (NEC) however this requires accurate prognostication early in the disease course. This study aims to identify and determine the effectiveness of previously reported methods or tests for the identification of surgical NEC.

Methods

Systematic review and meta-analysis with registration on PROSPERO including articles describing a method of identifying surgical NEC. Outcomes of interest were effectiveness and repeatability of index test.

Results

Of the 190 full-text articles screened, 90 studies were included which contained 114 methods of identifying surgical NEC in 9546 infants. Of these methods, 44 were a scoring system, 37 a single biomarker, 24 an imaging method, and 9

SUBMITTER: Bethell GS 

PROVIDER: S-EPMC11798840 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature