Mechanical power made simple: validating a simplified calculation of mechanical power in preterm lungs.

ABSTRACT:

Background

The incidence of chronic lung disease is increasing, suggesting a need to explore novel ways to understand ventilator induced lung injury (VILI) in preterm infants. Mechanical power (MP) is a unifying measure of energy transferred to the respiratory system and a proposed determinant of VILI. The gold-standard method for calculating MP (geometric method) is not feasible in the clinical setting. This has prompted the derivation of simplified equations for calculating MP.

Objective

To validate the agreement between a simplified calculation of MP (MP_Simple) and the true MP calculated using the geometric method (MP_Ref).

Methods

MP_Simple and MP_Ref was calculated in mechanically ventilated preterm lambs (n = 71) and the

SUBMITTER: Pearson-Lemme J 

PROVIDER: S-EPMC11798860 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature