Combining genotyping approaches improves resolution for association mapping: a case study in tropical maize under water stress conditions.

ABSTRACT: Genome-wide Association Studies (GWAS) identify genome variations related to specific phenotypes using Single Nucleotide Polymorphism (SNP) markers. Genotyping platforms like SNP-Array or sequencing-based techniques (GBS) can genotype samples with many SNPs. These approaches may bias tropical maize analyses due to reliance on the temperate line B73 as the reference genome. An alternative is a simulated genome called "Mock," adapted to the population using bioinformatics. Recent studies show SNP-Array, GBS, and Mock yield similar results for population structure, heterotic groups definition, tester selection, and genomic hybrid prediction. However, no studies have examined the results generated by these different genotyping approaches for GWAS. This study aims to test the equivalence among

SUBMITTER: de Pontes FCF 

PROVIDER: S-EPMC11798985 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature