Low-activity [¹⁸F]-somatostatin receptor (SSTR) imaging using [¹⁸F]SiTATE on a long axial field-of-view PET/CT scanner.

ABSTRACT:

Purpose

¹⁸F-labelled somatostatin receptor tracers have recently gained popularity due to their better spatial resolution, longer half-life and lower costs compared to ⁶⁸Ga-labeled tracers. The aim of this study was to evaluate the impact and limitations of reduced administered activities of [¹⁸F]SiTATE on image quality, lesion detectability and quantitative PET parameters in a long axial field-of-view (LAFOV) PET/CT scanner.

Methods

Twenty-four patients with histologically confirmed neuroendocrine tumor, who underwent clinically indicated [¹⁸F]SiTATE PET/CT examination (3.0 MBq/kg, 5 min PET scan time) on a Siemens Biograph Vision Quadra LAFOV PET/CT, were included retrospectively in this study. PET list-mode data were rebinned fo

SUBMITTER: Trautwein NF 

PROVIDER: S-EPMC11799470 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature