Case report: Local anesthesia with lidocaine infiltration for extended-release buprenorphine therapy.

ABSTRACT:

Background

Extended-release buprenorphine (BUP-XR) is a once-monthly subcutaneous injection for the treatment of opioid use disorder. Injection-site pain is a common adverse event reported with BUP-XR administration. Notwithstanding the advantages of BUP-XR, subjective pain and anxiety associated with injections can compromise patients' willingness to receive treatment. Lidocaine is an amide-type agent and sodium channel blocker commonly used for local and regional anesthesia in various fields of medicine.

Case presentation

We present two cases involving lidocaine infiltration to the induction phase of BUP-XR therapy in an outpatient setting. Prior to the intervention, 2 mL of 1% lidocaine was infiltrated subcutaneously at the sites of the planned needle insertion for a numb

SUBMITTER: Azar P 

PROVIDER: S-EPMC11799565 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature