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ABSTRACT: Objective
To assess whether individual diagnosis of low urinary iodine concentration (UIC) in pregnant women is associated with adverse maternal and neonatal outcomes.Methods
Studies that compared pregnant women with UIC <150 μg/L and those with UIC 150-249 μg/L were systematically reviewed. MEDLINE, Embase, LILACS and CENTRAL were our source databases. Selection of studies, risk-of-bias assessment and data extraction were performed in pairs and independently. Relative risk (RR) with 95% confidence interval (CI) was calculated as an estimate of the effect of iodine <150 μg/L. Stata software was used to perform meta-analyses. The quality of evidence was determined according to the Grading of Recommendations Assessment, Development and Evaluation.Results
In total, 700
SUBMITTER: Bolfi F
PROVIDER: S-EPMC11799753 | biostudies-literature | 2025 Mar
REPOSITORIES: biostudies-literature