Synthesis, crystal structure and Hirshfeld surface analysis of 5-oxo-<i>N</i>-phenyl-3-(thio-phen-2-yl)-2,3,4,5-tetra-hydro-[1,1'-biphen-yl]-4-carboxamide.

ABSTRACT: The asymmetric unit of the title com-pound, C₂₃H₁₉NO₂S, contains two mol-ecules that differ in the conformation of the two carb-ox-amide moieties. In the crystal, inter-molecular N-H⋯O hydrogen bonds link the mol-ecules into chains propagating parallel to the c-axis direction. Between the mol-ecules, weak C-H⋯π(ring) inter-actions are present, whereas π-π inter-actions are not observed. The Hirshfeld surface analysis of the crystal structure indicates that the most important contributions to the crystal packing are from H⋯H (47.6%), H⋯C/C⋯H (33.4%) and H⋯O/O⋯H (11.6%) inter-actions. Orientational disorder is observed for both thio-phene rings.

SUBMITTER: Aliyeva KN 

PROVIDER: S-EPMC11799798 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature