Cognitive Processing Therapy for Posttraumatic Stress Disorder in Japan: A Randomized Clinical Trial.

ABSTRACT:

Importance

Cognitive processing therapy (CPT) is an evidence-based treatment for posttraumatic stress disorder (PTSD). However, there is little evidence on the efficacy of CPT in East Asia.

Objective

To evaluate whether CPT is effective in treating PTSD among outpatients in a Japanese medical setting.

Design, setting, and participants

This randomized clinical trial used a 16-week, single-center, assessor-blinded, parallel-group superiority design to examine the efficacy of CPT in conjunction with treatment as usual (CPT-TAU) vs waiting list with TAU (WL-TAU) from April 2016 through December 2022. The trial included adult patients with PTSD at a national psychiatric referral hospital in Tokyo, Japan. Analysis was based on intention to treat and per protocol and was per

SUBMITTER: Ito M 

PROVIDER: S-EPMC11800015 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature