Direct Lawsone O-Alkylation Employing Sulfonic Acid-Functionalized Chitosan as a Biodegradable Organocatalyst.

ABSTRACT: An environmentally friendly, cheap, and scalable protocol for direct lawsone O-alkylation employing different alcohols using acid chitosan (CS-SO₃H) as a heterogeneous organocatalyst is described herein for the first time. A wide variety of alcohols can be converted with wide functional group tolerance and high atomic economy. Significantly, catalyst recycling and method chemoselectivity were also assessed.

SUBMITTER: de Jesus IS 

PROVIDER: S-EPMC11800155 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature