The atherogenic index of plasma increases the risk of incident kidney stones: a nested case-control study in Chinese adults.

ABSTRACT:

Objective

To investigate the association between atherogenic index of plasma (AIP) and risk of incident kidney stones.

Methods

A nested case-control study was conducted using data from the Shanghai Kidney Stone Cohort from December 2018 to February 2023. Kidney stones were ascertained by ultrasound. Propensity score matching selected 2,550 patients with incident kidney stones and 5,100 controls from a total of 64,121 adults. Baseline fasting plasma samples were collected to measure the AIP, defined as the logarithm of the ratio triglycerides to high-density lipoprotein cholesterol. A multivariable conditional logistic regression model and restricted cubic spline were applied to examine the association between the AIP and the risk of incident kidney stones.

Results

The

SUBMITTER: Wang D 

PROVIDER: S-EPMC11800335 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature