Triglyceride-glucose index and mortality risks in Helicobacter pylori-infected patients: a national cohort study.

ABSTRACT:

Background

While Helicobacter pylori (H. pylori) infection is associated with insulin resistance and higher mortality, research on insulin resistance indices and outcomes in H. pylori-infected patients is scarce. This study examines the association between the triglyceride-glucose (TyG) index, an insulin resistance marker, and all-cause and cardiovascular mortality in these patients.

Methods

This study analyzed NHANES 1999-2000 data to assess the association between the TyG index and all-cause and cardiovascular mortality in H. pylori-infected patients using weighted Cox models and restricted cubic spline analysis.

Results

Among 627 participants with a median follow-up of 20.8 years, 108 all-cause and 28 cardiovascular deaths occurred. Cox models showed that TyG was l

SUBMITTER: Cao Y 

PROVIDER: S-EPMC11800404 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature