Viral Burden and Illness Severity During Acute SARS-CoV-2 Infection Predict Persistent Long COVID Symptoms.

ABSTRACT:

Background

Long COVID is a common complication of infection with severe acute respiratory syndrome coronavirus 2, but the prevalence and predictors of the condition remain poorly characterized.

Methods

We prospectively studied adults (≥18 years) with acute coronavirus disease 2019 (COVID-19) presenting to an urban safety net hospital and associated clinics between July 2020 and December 2022. Logistic regression models were used to evaluate the association between baseline demographic, clinical, and laboratory characteristics with long COVID status, defined as symptoms persisting at least 9 months after acute disease. Among unrecovered participants, we describe the prevalence of individual symptoms.

Results

We enrolled 222 participants, 162 (73%) of whom had known rec

SUBMITTER: Brandstetter Figueroa E 

PROVIDER: S-EPMC11800476 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature