Treatment approaches for idiopathic retroperitoneal fibrosis: a systematic review with meta-analysis.

ABSTRACT:

Background

Currently, there is no standard therapy for idiopathic retroperitoneal fibrosis, so a systematic review was undertaken to assess the effectiveness of different treatment approaches.

Methods

A comprehensive search of English and German literature from 1980 to 2021 was conducted using PubMed, Embase, and PreMedline. To be included, studies must have had a minimum of two patients employing the same treatment approach and reporting relevant treatment outcomes. A meta-analysis with a subgroup analysis was conducted for the primary outcomes "regression of fibrosis," "freedom from ureteric stents" and "relapse rate," and the secondary outcome "clinical improvement." The lack of homogeneous data prevented a subgroup analysis for the primary outcome "improvement in renal f

SUBMITTER: Steimer A 

PROVIDER: S-EPMC11800648 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature