A biological model of nonlinear dimensionality reduction.

ABSTRACT: Obtaining appropriate low-dimensional representations from high-dimensional sensory inputs in an unsupervised manner is essential for straightforward downstream processing. Although nonlinear dimensionality reduction methods such as t-distributed stochastic neighbor embedding (t-SNE) have been developed, their implementation in simple biological circuits remains unclear. Here, we develop a biologically plausible dimensionality reduction algorithm compatible with t-SNE, which uses a simple three-layer feedforward network mimicking the Drosophila olfactory circuit. The proposed learning rule, described as three-factor Hebbian plasticity, is effective for datasets such as entangled rings and MNIST, comparable to t-SNE. We further show that the algorithm coul

SUBMITTER: Yoshida K 

PROVIDER: S-EPMC11801247 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature