Placental multimodal MRI prior to spontaneous preterm birth <32 weeks' gestation: An observational study.

ABSTRACT:

Objective

To utilise combined diffusion-relaxation MRI techniques to interrogate antenatal changes in the placenta prior to extreme preterm birth among both women with PPROM and membranes intact, and compare this to a control group who subsequently delivered at term.

Design

Observational study.

Setting

Tertiary Obstetric Unit, London, UK.

Population

Cases: pregnant women who subsequently spontaneously delivered a singleton pregnancy prior to 32 weeks' gestation without any other obstetric complications.

Controls

pregnant women who delivered an uncomplicated pregnancy at term.

Methods

All women consented to an MRI examination. A combined diffusion-relaxation MRI of the placenta was undertaken and analysed using fractional anisotropy, a combined T2*

SUBMITTER: Hall M 

PROVIDER: S-EPMC11801328 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature